Heart failure
Conditions
Interventions
Group A:The first 12 weeks: HIIT combined with oral iron supplementation and routine nursing
After 12 weeks: oral iron supplementation and routine nursing
Group B:The first 12 weeks: oral iron supplementation and routine nursing
The second 12 weeks: HIIT combined with oral iron supplementation and routine nursing
Sponsors
Shanghai Seventh People's Hospital
Eligibility
Sex/Gender
All
Age
50 Years to 80 Years
Inclusion criteria
Inclusion criteria: (1) The New York Heart Association (NYHA) cardiac function grade II-III; (2) Independent activities of daily living before admission (ADL) (3) Self-guided walking distance of more than 4 meters after admission (walkers can be used) (4) Age above 50 and below 80 (5) Serum ferritin <100µg/L or 100 -- 300µg/L, transferrin saturation (TSAT) <20% (6) Participate in the study voluntarily and sign the informed consent.
Exclusion criteria
Exclusion criteria: (1) Advanced heart failure (requiring a heart transplant or left ventricular assist device within 6 months); (2) Patients with primary valvular disease (such as severe aortic stenosis or mitral insufficiency); (3) Advanced renal insufficiency (estimated glomerular filtration rate 160/100 mmHg); (6) infection, inflammatory disease or active neoplastic disease (7) severe liver insufficiency (transaminase) = 3 times the upper limit of normal value); (8) Polycythemia (hemoglobin >16 g/dL). (9) The patient has obvious cognitive impairment; (10) Patients had poor compliance or could not communicate normally.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Grading of heart function;Serum ferritin; | — |
Secondary
| Measure | Time frame |
|---|---|
| 6MWT;NT-proBNP;KCCQ; | — |
Countries
China
Contacts
Public ContactWU Xu-bo
Shanghai Seventh People's Hospital
Outcome results
None listed