Coronary atherosclerotic heart disease
Conditions
Interventions
ESPB group:erector spinae plane block+Inject 0.375% ropivacaine 20ml/side
C group:erector spinae plane block+Inject 0.9% normal saline with equal volume
Sponsors
Jining No1. People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 90 Years
Inclusion criteria
Inclusion criteria: Adult patients planning median sternotomy for off-pump coronary artery bypass grafting.
Exclusion criteria
Exclusion criteria: Refusal to participate, inability to cooperate in nerve block operation, emergency operation, cognitive impairment, severe heart failure (EF<35%), local anesthetic (LA) allergy, non steroid anti-inflammatory sensitivity, renal failure, respiratory failure, long-term history of opioid use, chronic pain syndrome, peripheral neuropathy, pregnancy, coexisting blood diseases, reduced blood volume, autoimmune diseases Patients with corticosteroid therapy or immunosuppressive therapy and language disorders.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Total amount of sufentanil used during operation; | — |
Secondary
| Measure | Time frame |
|---|---|
| Adverse reactions related to EPSB, such as pneumothorax, local anesthetic poisoning, infection of puncture site, etc;Opioid related events, such as time of mechanical ventilation, time of cardiac surgery intensive care unit, nausea, vomiting, and urinary retention.;VAS score at extubation and 3h, 6h, 12h and 24h after extubation (static and dynamic);IL-1, IL-6 and TNF before anesthesia induction, 5 minutes after sternotomy, at the end of surgery, 1 day after surgery, and 2 days after surgery- a Changes.;Patient satisfaction 24 hours after surgery; | — |
Countries
China
Contacts
Public ContactWenzhu Wang
Jining No1. People's Hospital
Outcome results
None listed