cervical incompetence
Conditions
Interventions
Cerclage group:cervical cerclage
control group:Vaginal progesterone
sample colection:No.
Sponsors
Shanghai East Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Cohort study. ? All pregnant women who attended our hospital during the study period and had their delivery cards established. ? Voluntary participation in this study and signing of informed consent form. 2. RCT study. ? Singleton pregnancies between 24 and 28 weeks of gestation. (ii) History of one or two previous midtrimester miscarriages or preterm deliveries at 16-34 weeks of gestation. (iii) cervical length =25 mm on transvaginal ultrasound. ? Voluntary participation in this study and signing of the informed consent form. Note: The study was included if both of the above conditions were met 3. To explore the predictive value of PYGL in cervical mucus for CI. ? All pregnant women who attended our hospital during the study period and had their delivery cards established. ? Voluntary participation in this study and signing of the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Cohort study. ? High sequence multiple pregnancies. ? with mental illness or cognitive impairment. 2. RCT studies. ? Those with painless cervical dilatation. ? active contractions. ? chorioamnionitis. ? abnormal antepartum hemorrhage. ? premature rupture of membranes. (6) Fatal fetal malformation or stillbirth. (7) Severe obstetric complications or comorbidities. ? Cervical cerclage or placement of a cervical support has been performed before or during pregnancy. Note: Subjects who meet any of the above criteria should be excluded. 3. To explore the predictive value of PYGL in cervical mucus for CI. ? High sequence of multiple pregnancies. ? Suffering from mental illness or cognitive impairment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Diagnosis until the gestational interval; | — |
Secondary
| Measure | Time frame |
|---|---|
| Gestational age of delivery;perinatal mortality rate;neonate birth weight;postpartum hemorrhage;laceration of cervix; | — |
Countries
China
Contacts
Public ContactMing Liu
Shanghai East Hospital (East Hospital Affiliated to Tongji University)
Outcome results
None listed