lower extremity lymphedema
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1)Age range 18 to 65 years old; (2)Secondary lymphedema of unilateral lower extremities; (3)Lymphedema stage I and II (4)Limb circumference greater than 2cm or volume increased by more than 10% compared with contralateral; (5)Consent to sign the informed consent form
Exclusion criteria
Exclusion criteria: (1)Simultaneous lymphedema in both extremities; (2)Primary lymphedema; (3)CDT treatment within 12 months; (4)Pregnant or lactating female subjects; (5)Severe heart and kidney disease; (6)A history of deep vein thrombosis or phlebitis; (7)Limb infection or severe ulceration; (8)Use any medication that affects body fluids and electrolytes; (9)Other conditions considered by the investigator to be inappropriate for participation in the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Reduction rate of edema of affected limb; | — |
Secondary
| Measure | Time frame |
|---|---|
| Ultrasound popliteal blood flow;Proprioception of knee joint;Quadriceps and triceps muscle strength;Knee and ankle joint range of motion;Score of subjective symptoms (heaviness, abnormality, pain);LYMQOL Chinese version of questionnaire scores; | — |
Countries
China
Contacts
Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School