Stroke
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: ? The patients was the first episode of ischemic stroke, and the disease course was less than 2 months; ? Age 45-80 years; ? Primary school education or above; ? No history of mental illness or cognitive impairment; ? The patients can cooperate with related scale evaluation; ? The patients had different degrees of motor, cognitive, speech and swallowing dysfunction; ? The affected limb (upper and lower limbs) Brunnstrom classification: II- ?grade; ?The patients agreed to participate in the study voluntarily and were able to complete the treatment.
Exclusion criteria
Exclusion criteria: ? Patients who had a history of psychoactive drug abuse or long-term heavy drinking; ? Recent use of drugs affecting cognitive function or anxiety and depression; ? Unable to complete the scale test; ? Hypofunction or failure of heart, lung, liver, kidney and other important organs; ? Patients can not tolerate enriched rehabilitation training and transcranial magnetic stimulation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fugl-Meyer Motor Function Rating Scale;Montreal Cognitive Assessment;Aphasia Rating Scale;Swallowing Dysfunction Rating Scale;Motor threshold;fMRI;Inflammatory cytokines;amino acid; | — |
Countries
China
Contacts
Northern Jiangsu People's Hospital /Clinical Medical College, Yangzhou University