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Investigation of Pulmonary Mechanics, Radiological and Biological Factors Associated With Phenotypes and Outcomes in Acute Respiratory Failure Patients With Mechanical Ventilation: a Multicentre, Prospective, Observational, Longitudinal Cohort Study

Investigation of Pulmonary Mechanics, Radiological and Biological Factors Associated With Phenotypes and Outcomes in Acute Respiratory Failure Patients With Mechanical Ventilation: a Multicentre, Prospective, Observational, Longitudinal Cohort Study

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2200066860
Enrollment
Unknown
Registered
2022-12-20
Start date
2022-12-15
Completion date
Unknown
Last updated
2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Respiratory Failure

Interventions

Phenotypes A:None
Phenotypes B:None
Phenotypes C:None

Sponsors

The First Affiliated hospital of Soochow University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 100 Years

Inclusion criteria

Inclusion criteria: 1.Acute respiratory failure (PaO2/FiO2=300mmHg); 2.Receiving invasive mechanical ventialtion

Exclusion criteria

Exclusion criteria: 1. Age<18yrs; 2. Patient who receiving mechanical ventialtion for less than 24 hours; 3. For patients who admitted to ICU morethan once, we only include the first record of ICU admission; 4. Patients have been included in other centers

Design outcomes

Primary

MeasureTime frame
28-day all cause mortality;—

Secondary

MeasureTime frame
Ventilator free days in 28-day;ICU mortality;30-day mortality after liberating from PPV;The rate of successful weaning within 30-days after liberating from PPV;Incidence rate of organ dysfunction;Length of ICU stay;—

Countries

China

Contacts

Public ContactHui Chen

The First Affiliated hospital of Soochow University

15905162429@163.com18006138640

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026