myopia,dry eye
Conditions
Interventions
one:3% Diquafosol Ophthalmic Solution
two:3% Diquafosol Ophthalmic Solution+Wearing Orthkeratology
Sponsors
Changsha Aier Eye Hospital
Eligibility
Sex/Gender
All
Age
8 Years to 18 Years
Inclusion criteria
Inclusion criteria: (1) Age > 8 years; (2) myopia from ?1.0D to ?5.5 DS, and with-the-rule astigmatism of up to ?1.75 DC or against-the-rule astigmatism of <-0.75 DC with keratometry from 41 to 46 D; (3) For the OrthoK wearers group, patients should have been able to master the wearing of OOK lenses and had worn them for 1 year; and (4) for the OrthoK Candidates group, all patients were the first time for orthkeratology and wore no glasses and contact lenses or used mainly frames before.(5) Participants with mild to moderate dry eye based on NIKTMH < 0.20mm or NIKBUT < 10s from Keratograph 5M examination adopted by the Dry Eye Workshop (DEWS) report were included
Exclusion criteria
Exclusion criteria: Participants who were had pathological changes of the lid margin or cornea, uvea, or retina, had other systemic diseases that may influence the ocular surface, and received other ocular treatment or surgeries.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Tear Film Break-up Time;Tear Meniscus Height;Dry Eye Questionnaire-5;blink pattern;meibomian gland score; | — |
Countries
China
Contacts
Public ContactYang Zhikuan
Outcome results
None listed