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Mechanism exploration and efficacy verification of electroacupuncture regulating reticulospinal tract remodeling to promote upper limb motor recovery after stroke

Mechanism exploration and efficacy verification of electroacupuncture regulating reticulospinal tract remodeling to promote upper limb motor recovery after stroke

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200066858
Enrollment
Unknown
Registered
2022-12-20
Start date
2022-12-20
Completion date
Unknown
Last updated
2023-05-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Stroke

Interventions

experimental group:elctroacupuncture(Hegu+Quchi)and conventional therapies
control group:conventional therapies

Sponsors

Tongji Hospital affiliated to Tongji Medical College,Huazhong University of Science and Technology
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: (1) aged 18-70 years old, male or female; (2) first onset of stroke at 6 months(lesions involving unilateral cortex or basal ganglia, but not brainstem or cerebellum) diagnosed by Symptoms and imaging findings; (3) Sitting balance level 2, and can complete 30° shoulder forward bend in the seated position (4) existing upper limb motor dysfunction, and the Fugl-Meyer Assessment for the Upper Extremity is 15-55 points; (5)no obvious discomfort for 114dB sudden sound; (5) able to compliance simple instruction; (6)No obvious discomfort to electroacupuncture stimulation; (7)Have certain cognitive learning ability, can follow simple instructions; (8)voluntarily participate in the trial and sign an informed consent form.

Exclusion criteria

Exclusion criteria: (1)Previous history of stroke; (2) apparent muscle spasticity with MAS score=3; (3) any condition that severely restricts the movement of upper and lower limbs, such as joint muscle contracture, severely frozen shoulder, fracture, arthritis, skin ulcers, pressure sores at treatment sites, recent surgical incisions or active skin diseases, coagulopathy, bleeding tendency, etc; (4) implant a cardiac pacemaker or other electronic instruments; (5) Severe cognitive impairment and inability to communicate effectively with medical staff; (6)A history of orthopedic surgery, rheumatism or other diseases that restrict the movement of the upper and lower limbs; (7)Other conditions considered inappropriate by the investigator (e.g. severe hypertension, coronary heart disease, etc.)

Design outcomes

Primary

MeasureTime frame
AMAs of trunk and upper limb acquired from sEMG;

Secondary

MeasureTime frame
Reaching Performance Scale for Stroke (RPSS);Fugl-Meyer Assessment for the Upper Extremity (FMA-UE);Modified Barthel Index (MBI);World Health Organization Disability Assessment Schedule Version 2.0 (WHODAS 2.0);functional near-infrared spectroscopy (fNIRS);

Countries

China

Contacts

Public ContactXiaohua Han

Tongji Hospital affiliated to Tongji Medical College,Huazhong University of Science and Technology

hanxiao1470@hust.edu.cn+86 132 9790 6483

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026