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The clinical outcome of fresh embryo transfer in antagonist cycles may benefit from GnRH-a combined with HCG trigger

The clinical outcome of fresh embryo transfer in antagonist cycles may benefit from GnRH-a combined with HCG trigger

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200066833
Enrollment
Unknown
Registered
2022-12-19
Start date
2023-01-01
Completion date
Unknown
Last updated
2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

female infertility

Interventions

Test Group: GnRH-a combined with HCG trigger
Control group:HCG trigger

Sponsors

Henan Provincial People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: 1. COS cycle of the first or second antagonist protocol; 2. Age =40 years old; 3. BMI 30 kg/m2 or less; 4. AMH acuity 1.2 ng/ml; 5. 7-15 dominant follicles on trigger day;

Exclusion criteria

Exclusion criteria: 1. The PGT cycle; 2. Endometrial thickness < 8mm on trigger day, or previous uterine or endometrial lesions, hydrosalpinx; 3. =2 previous failed ET cycles (no clinical pregnancy after transplantation); 4. Patients with abnormal symptoms in stage III-IV; 5. Egg freezing cycle; 6. Patients unable to undergo fresh cycle transplantation due to various factors.

Design outcomes

Primary

MeasureTime frame
clinical pregnancy rate;live birth rate;—

Countries

China

Contacts

Public ContactShaodi Zhang

Henan Provincial People's Hospital

zhangshd@126.com15838067326

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026