Observation of postoperative analgesic effect of Transversus Abdominis Plane Block combined with Rectus sheath block in patients undergoing Breast Reconstruction by DIEP Flap

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2200066825

Enrollment

Unknown

Registered

2022-12-19

Start date

2022-12-19

Completion date

Unknown

Last updated

2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients with breast reconstruction by DIEP Flap

Interventions

Group A:TAP+RSB

Group B:No nerve block

Eligibility

Sex/Gender

Female

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: The women undergoing elective breast reconstruction by DIEP flap, aged 18-60 year-old, ASA grade I-?

Exclusion criteria

Exclusion criteria: (1) a history of long-term use of analgesics (such as opioids, acetaminophen or non-steroidal anti-inflammatory drugs); (2) history of abnormal coagulation; (3) allergic to the drug to be used; (4) Skin infection at the puncture site of nerve block (5) language and mental disorders and unable to complete the pain score and postoperative recovery quality score

Design outcomes

Primary

Measure	Time frame
QoR-15 score;	—

Secondary

Measure	Time frame
resting, coughing pain scores;Sufentanil consumption in the first 24 hours after surgery;Use of oral remedial analgesics;Patient satisfaction with analgesia;Opioid side effects(nausea and vomiting?Dizziness?pruritus?sleepiness?respiratory depression,etc);Nerve block- related complications(visceral injury, nerve injury, local anesthetic poisoning, etc.);time to ambulation;Intraoperative dosage of propofol and remifentanil;Ramsay score;Intraoperative blood pressure, heart rate, SPO2, BIS, end-expiratory carbon dioxide;Surgery duration?Extubation duration;hospital stay duration;	—

Measure

Time frame

resting, coughing pain scores;Sufentanil consumption in the first 24 hours after surgery;Use of oral remedial analgesics;Patient satisfaction with analgesia;Opioid side effects(nausea and vomiting?Dizziness?pruritus?sleepiness?respiratory depression,etc);Nerve block- related complications(visceral injury, nerve injury, local anesthetic poisoning, etc.);time to ambulation;Intraoperative dosage of propofol and remifentanil;Ramsay score;Intraoperative blood pressure, heart rate, SPO2, BIS, end-expiratory carbon dioxide;Surgery duration?Extubation duration;hospital stay duration;

—

Countries

China

Contacts

Public ContactChunmei Chen

Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College

chunmeichen2008@163.com+8618611612186

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026