Benefit and risk assessment of preoperative use of low-molecular-weight heparin to prevent venous thrombosis in elderly patients with unstable intertrochanteric fractures

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2200066819

Enrollment

Unknown

Registered

2022-12-19

Start date

2023-01-01

Completion date

Unknown

Last updated

2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Unstable intertrochanteric fractures in the elderly

Interventions

LMWH preoperative group:Low-molecular-weight heparin

LMWH postoperative group:Physiological saline preoperation and LMWH postoperation

Eligibility

Sex/Gender

All

Age

65 Years to No maximum

Inclusion criteria

Inclusion criteria: Age 65 or older; Unstable intertrochanteric fracture is treated by intramedullary nail internal fixation (unstable intertrochanteric fracture is defined as A2.2-3.3 in AO/OTA classification).

Exclusion criteria

Exclusion criteria: Preoperative examination revealed deep venous thrombosis of the lower extremities; The preoperative hemoglobin is less than 80g/L; Pathological fracture; Multiple fractures with another part of the fracture needs surgical treatment; There are contraindications for anticoagulant therapy; The time from injury to admission is more than 3 days.

Design outcomes

Primary

Measure	Time frame
VTE incidence;Total perioperative blood loss;	—

Secondary

Measure	Time frame
Major bleeding event;Blood transfusion rate;Mortality rate in 3 months after operation;	—

Countries

China

Contacts

Public ContactXiangping Luo

Hengyang Central Hospital

luoxiangping8@sina.com18692028736

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026