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Effect of anterior iliopsoas space block preventive analgesia on stress response and postoperative cognitive function in elderly patients with hip fracture

Effect of anterior iliopsoas space block preventive analgesia on stress response and postoperative cognitive function in elderly patients with hip fracture

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200066797
Enrollment
Unknown
Registered
2022-12-17
Start date
2022-12-17
Completion date
Unknown
Last updated
2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hip fracture in elderly patients

Interventions

Group Q:anterior iliopsoas muscle space block
Group C:subarachnoid block
Minimum effective concentration group:anterior iliopsoas muscle space block
Minimum effective capacity group:anterior iliopsoas muscle space block

Sponsors

Affiliated Hospital of Jiangsu University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
65 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Patients who are scheduled for elective surgical treatment of hip fractures, the types of surgery include total hip replacement or hemi-hip replacement, PFNA (proximal femoral anti-rotation intramedullary nail fixation), American Society of Anesthesiologists (ASA) grade II to III ; 2. Aged >= 65 years, BMI 18-25; 3. Agree to receive preventive analgesia; 4. Voluntary participation in research.

Exclusion criteria

Exclusion criteria: 1. Significant cognitive impairment was found in the preoperative visit (MMSE score (see Table 2) illiterate < 17 points, primary school < 20 points, junior high school and above <24 points); 2. History of hip surgery; 3. History of opioid or alcohol abuse; 4. History of chronic pain; 5. Nervous system diseases; 6. Severe visual impairment; 7. Anemia (Hb < 80g/L), coagulation disorder; 8. Inability to communicate effectively with doctors; 9. Voluntary withdrawal study; 10. Patients with underlying diseases such as heart failure, severely reduced respiratory function, severe arrhythmia, poorly controlled hypertension and diabetes before surgery.

Design outcomes

Primary

MeasureTime frame
VAS score;Plasma glucocorticoid concentration;Perioperative delirium incidence;

Secondary

MeasureTime frame
Sleep quality;PCIA press number;Adverse effects associated with analgesias;Heart rate;Mean arterial pressure;

Countries

China

Contacts

Public ContactMa Peng

Affiliated Hospital of Jiangsu University

ujsmp@163.com+86 13952869805

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026