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Effect of acellular matrix peripheral nerve repair membrane on protection and repair of inferior alveolar nerve exposure during oral surgery

Effect of acellular matrix peripheral nerve repair membrane on protection and repair of inferior alveolar nerve exposure during oral surgery

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200066788
Enrollment
Unknown
Registered
2022-12-16
Start date
2023-01-01
Completion date
Unknown
Last updated
2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

exposure of inferior alveolar nerve

Interventions

Test group:Acellular nerve repair membrane+collagen material
Control group:Collagen material

Sponsors

Hospital of Stomatology, Wuhan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: ? Preoperative CBCT has confirmed that the surgical area involves the mandibular canal where the inferior alveolar nerve is located (FIG. 2), or the exposed cases of the inferior alveolar nerve were found during oral surgery. ? Aged between 18 and 60 years old; 3) No history of drug or food allergy; ? no mental illness; No history of serious cardiovascular and cerebrovascular diseases; There was no history of trigeminal neuralgia and no numbness of bilateral lower lip before surgery. There were no other potential factors in oral cavity that may cause inferior alveolar nerve injury before surgery, including tumor, trauma, inflammation, etc. ? Patients who are willing to participate in this experiment and sign informed consent.

Exclusion criteria

Exclusion criteria: On the basis that the inclusion criteria are not met ? The patient with collagen allergy should not use it; ? The use site has infectious inflammation should not be prohibited; ? Uncontrolled diseases, such as diabetes, rickets, thyroid diseases, severe liver and kidney dysfunction; ? Long-term adrenocortical hormone therapy; ? Autoimmune diseases; ? Undergoing radiation therapy; ? Serious smoking habits; ? are clinically diagnosed as mental anxiety, hypersensitivity patients; ? Patients who are not willing to participate in this study, or other cases that the investigator deems unsuitable for inclusion.

Design outcomes

Primary

MeasureTime frame
Symptoms of nerve numbness;

Countries

China

Contacts

Public ContactRui Sun

School & Hospital of Stomatology, Wuhan University

sunrui12@whu.edu.cn+86 27 87686386

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026