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Clinical exploration of the value of dynamic monitoring of peripheral circulating new circular RNA circ_0081001 based on ddPCR technology for early diagnosis of osteosarcoma chemotherapy resistance and lung metastasis

Clinical exploration of the value of dynamic monitoring of peripheral circulating new circular RNA circ_0081001 based on ddPCR technology for early diagnosis of osteosarcoma chemotherapy resistance and lung metastasis

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2200066770
Enrollment
Unknown
Registered
2022-12-16
Start date
2023-01-01
Completion date
Unknown
Last updated
2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Osteosarcoma

Interventions

Observation group:/

Sponsors

Shanghai Tenth People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
6 Years to 70 Years

Inclusion criteria

Inclusion criteria: (1) Osteosarcoma with a clear pathological diagnosis; (2) Expected survival period of more than 1 year; (3) Can tolerate surgery or chemotherapy, targeted therapy, immunotherapy and other treatment options; (4) Agree with tumor tissue and blood samples acquisition.

Exclusion criteria

Exclusion criteria: (1) Tumors of other pathological types; (2) Combined with other types of tumors; (3) Reject the aforementioned informed consent.

Design outcomes

Primary

MeasureTime frame
Tumor necrosis;Lung Metastases;overall survival;local recurrence rate;—

Secondary

MeasureTime frame
Enneking staging;Tumor Volume;—

Countries

China

Contacts

Public ContactZhu Kun-Peng

Shanghai Tenth People's Hospital

892921732@qq.com15216636683

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026