shock patients
Conditions
Interventions
etomidate:etomidate 0.1mg/(kg*min)
Sponsors
Fisrt Hospital of Putian, Putian,Fujian
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1)Age over 18 years; 2) American Society of Anesthesiologists (ASA) classification II–III; 3) Shock patients:0.7<shock index<2.0;4) Emergency operation under general anesthesia.
Exclusion criteria
Exclusion criteria: 1)Severe shock or dying person with shock index = 2.0;2)Cardiac insufficiency (EF<40% or NYHA classification III to IV); 3) arrhythmias (such as second- or third-degree atrioventricular block or atrial fibrillation); 4) unstable ischemic heart disease; 5) valvular heart disease with significant hemodynamic fluctuations;6) received pacemaker implantation; 7) body mass index more than 30; 8) predicted or history of difficulty airway; 9) pyloric or high intestinal obstruction; 10) allergic or contraindications to study drugs; 11) history of drug or alcohol abuse; 12) any other conditions that precluded participation judged by the primary investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Area under the baseline MAP over the first 15 min after induction;the baseline CI over the first 15 min after induction;the baseline SVV over the first 15 min after induction; | — |
Secondary
| Measure | Time frame |
|---|---|
| the baseline HR over the first 15 min after induction;Dosage of vasoactive drugs over the first 15 min after induction;Time to loss of consciousness;BIS values at the time of loss of consciousness; | — |
Countries
China
Contacts
Public ContactShurong Li
Fisrt Hospital of Putian, Putian,Fujian
Outcome results
None listed