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Effects of S-ketamine on postoperative sleep in patients undergoing thoracoscopic surgery

Effects of S-ketamine on postoperative sleep in patients undergoing thoracoscopic surgery

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200066742
Enrollment
Unknown
Registered
2022-12-15
Start date
2022-12-31
Completion date
Unknown
Last updated
2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative sleep disturbance

Interventions

S-ketamine group:a bolus of 0.5 mg/kg of S-ketamine during the period of anesthesia induction followed by 0.1mg/kg/h intravenous infusion until 15 minutes before the end of surgery
Control group:a bolus of 0.5 mg/kg of normal saline during the period of anesthesia induction followed by 0.1mg/kg/h intravenous infusion until 15 minutes before the end of surgery

Sponsors

Hebei General Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: Individuals were considered eligible when satisfying the inclusion criteria: patients undergoing elective thoracoscopic surgery with ASA grade II-III, aged 18 or older, and body mass index (BMI) of 18~32 kg/m2

Exclusion criteria

Exclusion criteria: The exclusion standards included: serious cardiovascular and cerebrovascular diseases, severe?hepatic and?renal?dysfunction, a known history of mental illness, depression or sleep disorders (PSQI scores >7), contraindication and/or allergic to S-ketamine, patients who refused, and the surgical duration=3 hours.

Design outcomes

Primary

MeasureTime frame
Richard Campbell Sleep Questionnaire;

Countries

China

Contacts

Public ContactRong Junfang

Hebei General Hospital

rjf13291@163.com18633927777

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026