Obstructive sleep apnea hypopnea syndrom,OSAHS
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) OSAHS diagnosed by polysomnography (PSG), which meets the relevant diagnostic criteria of OSAHS in the Guidelines for the Diagnosis and Treatment of Obstructive Sleep Apnea Hypopnea Syndrome (2011 Revision); (2) In line with the surgical indications, uvulopalatopharyngoplasty was performed; (3) Age 18-65 years old; (4) Good communication and comprehension skills, voluntarily participate in this study, and sign an informed consent form.
Exclusion criteria
Exclusion criteria: (1) Patients with severe cardiopulmonary diseases, malignant tumors or other serious organ diseases; (2) long-term heavy drinking and/or taking sedative-hypnotic or muscle relaxant drugs; (3) Patients with mental illness or cognitive dysfunction.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| lowest oxygen saturation levels,LSaO2; | — |
Secondary
| Measure | Time frame |
|---|---|
| apnea hypopnea index, AHI;average oxygen saturation, AO2;respiratory disturbance index,RDI;oxygen desaturation index, ODI;oxygen saturation level <90%,TS90%;longest apnea time, LAT;high-sensitivity C-reactive protein levels, hs-CRP;tumor necrosis factor alpha levels, TNF-a ;interleukin 10 levels, IL-10;orofacial myofunction;Neck circumference; | — |
Countries
China
Contacts
School of Nursing, Chongqing Medical University