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Effect of photodynamic therapy on soft tissue healing after tooth extraction at periodontal infection sites: a randomized controlled clinical trial

Effect of photodynamic therapy on soft tissue healing after tooth extraction at periodontal infection sites: a randomized controlled clinical trial

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200066735
Enrollment
Unknown
Registered
2022-12-15
Start date
2022-12-15
Completion date
Unknown
Last updated
2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

periodontitis

Interventions

Experimental group:Photodynamic therapy assisted debridement of tooth extraction sockets
control group:None (Routine debridement of extraction sockets)

Sponsors

The Affiliated Stomatology Hospital of Zhejiang University School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: (1) Age range from 18 to 65 years old; (2) Patients with extensive periodontitis of the whole mouth; (3) There was a deep periodontal pocket with PD=5mm and at least one adjacent tooth at the extraction site; (4) Periodontitis was controlled, and the extraction site and adjacent teeth were not in the acute inflammation or infection stage; (5) The extraction site has a hopeless prognosis or no preservation value, and it is the first and second molars or maxillary wisdom teeth that erupt in a positive position

Exclusion criteria

Exclusion criteria: (1) pregnant and lactating women; (2) patients with systemic diseases that may affect the ability of postoperative healing (such as patients with radiotherapy and chemotherapy, history of hematological diseases, and uncontrolled disease) Diabetes mellitus, etc.); (3) long-term use of drugs known to affect bone metabolism or mucosal healing such as bisphosphonates and non-steroidal anti-inflammatory drugs; (4) smoking > 10 cigarettes per day; (5) root breakage or gingival tear occurred during tooth extraction.

Design outcomes

Primary

MeasureTime frame
Wound healing rate;

Secondary

MeasureTime frame
Landry, Turnbull and Howley soft tissue healing index;Degree of pain;Changes in Bone Mineral density;Bone height changes;

Countries

China

Contacts

Public ContactPeihui Ding

The Affiliated Stomatology Hospital of Zhejiang University School of Medicine

phding@zju.edu.cn+86 13738187965

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026