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Relationship between corneal biomechanical changes and early diagnosis of POAG

Corneal biomechanical changes and early diagnosis of POAG

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2200066730
Enrollment
Unknown
Registered
2022-12-14
Start date
2022-12-30
Completion date
Unknown
Last updated
2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

glaucoma

Interventions

High IOP group:none
control group:none

Sponsors

West China Hospital of Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Patients diagnosed according to the Chinese Glaucoma Guidelines (2020) and POAG diagnostic criteria were selected (1). High IOP group (100 eyes): corrected visual acuity = 0.6, diopter = ± 6.00D; Other than glaucoma, no other eye disease, eye trauma or surgical history. (2).NTG group (100 eyes): corrected visual acuity = 0.6, diopter = ±6.00 D; Other than glaucoma, no other eye disease, eye trauma or surgical history. (3). Normal volunteers group (100 eyes): non-glaucoma patients selected for ICL refractive correction, and the eyes Examination: corrected visual acuity =0.8, diopter = ±6.00 D; Intraocular pressure = 21 mmHg; Depending on the nipple cup plate ratio < 0.5, difference between eyes < 0.2, no diffuse or local disk edge narrowing; No family history of glaucoma.

Exclusion criteria

Exclusion criteria: Exclusion criteria Angle closure glaucoma, cornea has obvious turbidity (edema, clouding, pall, white spots, to corneal density measurement > 30 is the standard); Contact lens wearers; People with high myopia may have undergone refractive surgery; Patients with eye trauma or past intraocular surgery, systemic or topical use of corticosteroids, other acute or chronic eye diseases that may affect corneal biological or physical properties, and any systemic or ocular lesions that may affect CCT, IOP measurement and visual field examination. Pregnant and lactating women, persons with mental diseases and disabilities according to medical judgment, persons who do not want to cooperate with the examination due to subjective reasons or cannot cooperate with the examination due to objective conditions.

Design outcomes

Primary

MeasureTime frame
bIOP;IOP;CCT;

Secondary

MeasureTime frame
uncorrected visual acuity(UCVA);Vision field;

Countries

China

Contacts

Public ContactJing Tang

The Department of Ophthalmology,West China Hospital of Sichuan University

tangjing0802@163.com013258339950

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026