stroke
Conditions
Interventions
Stroke patients group:Conventional grasping under normal visual feedback
Active sensory grasping with normal visual feedback
Conventional grasping under mirror visual feedback
Active sensory grasping under mirror visual feedback
Healthy subjects group:Conventional grasping under normal visual feedback
Sponsors
Huashan Hospital Affiliated to Fudan University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Healthy subjects: ? Age 18-80 years; ? Right handed; ? Normal vision or corrected vision; ? No previous history of nervous system diseases, musculoskeletal system diseases, and other important organ injuries; ? No abnormal symptoms, such as cognitive and intellectual disorders; ? Volunteer to participate in this study, and sign the informed consent form by himself or his immediate family on behalf. 2. Subjects with stroke: ? aged 18-80 years, right-handed, with normal vision or corrected vision; ? The first and unilateral cerebral hemorrhage/cerebral infarction was confirmed by computed tomography (CT) or magnetic resonance imaging (MRI); ? The diagnosis was in line with the standard of Diagnostic Essentials of Major Cerebrovascular Diseases in China 2019 formulated by the Cerebrovascular Disease Group of the Neurological Branch of the Chinese Medical Association; ? The onset time was 1 week to 6 months, and the condition was stable; ? No cognitive impairment, MoCA score = 22, can cooperate with evaluation and treatment; ? First accepted mirror therapy; ? Brunnstrom stage of upper limb and hand was between stage ? and stage ?, and the major flexors of wrist and elbow were not accompanied with severe spasms, including muscle tension of wrist flexors and biceps brachii = 2 (modified Ashworth scale); ? It can be kept in a sitting position for at least 60 minutes; ? Volunteer to participate in this study, and sign the informed consent form by himself or his immediate family on behalf.
Exclusion criteria
Exclusion criteria: 1. Healthy subjects: ? upper limb trauma or strain disorder occurred within 2 weeks before the experiment; ? Other clinical experimenters at the same time; ? Those who are allergic to conductive paste, scrub paste and other test related equipment and components; ? Those who cannot complete the test and have poor compliance. 2. Subjects with stroke:: ? The condition worsens, and new infarcts or large cerebral infarction occur; ? Previous history of epilepsy, cerebral hemorrhage and serious heart, lung, liver, kidney and other important organs Functional failure, uncontrollable hypertension, arrhythmia, severe coronary heart disease, and poor control of diabetes complications; ? Other central nervous regulation technologies, such as brain computer interface technology, transcranial electrical stimulation technology, motor imagination therapy and other intervention tests are being conducted; ? Those who are allergic to conductive paste, scrub paste and other test related equipment and components; ? Contraindications of neuroelectrophysiological examination and magnetic resonance examination, such as claustrophobia, wearing a cardiac pacemaker, intracranial metal implants or skull defects, pregnancy, lactation, or childbearing women without reliable contraceptive measures; ? Those who cannot complete the test and have poor compliance.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Electroencephalography assessment; | — |
Secondary
| Measure | Time frame |
|---|---|
| Subjective feedback questionnaire; | — |
Countries
China
Contacts
Public ContactJia Jie
Huashan Hospital Affiliated to Fudan University
Outcome results
None listed