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The effect of rehabilitation robot-assisted training combined with intermittent theta burst stimulation on the upper limb motor function of stroke patients and the neural mechanism

Rehabilitation Medicine and Physical Therapy

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200066702
Enrollment
Unknown
Registered
2022-12-14
Start date
2022-12-19
Completion date
Unknown
Last updated
2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

stroke

Interventions

Experimental group:Intermittent theta burst stimulation and robot-assisted upper-limb training
control group :Robot-assisted upper-limb training

Sponsors

Zhejiang Rehabilitation Medical Center
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: (1) Meet the diagnostic criteria for stroke (symptoms and signs, imaging indicators, etc.); brain hemorrhage diagnosis according to the China Brain Hemorrhage Diagnosis and Treatment Guidelines 2019 and ischemic stroke diagnosis according to the China Acute Ischemic Stroke Diagnosis and Treatment Guidelines 2018. (2) Age of 18-80 years, first onset, and duration of disease within 6 months after stroke onset. (3) Patients with modified Ashworth classification of upper extremity 20). (7) No severe limitation in the range of motion of the shoulder and elbow joints and no severe shoulder pain. (8) Stable medical condition. (9) Signed informed consent.

Exclusion criteria

Exclusion criteria: (1) Those with severe cognitive impairment or behavioral impairment who are unable to cooperate with the training. (2) Those with severe bone and joint disease, severe cardiopulmonary dysfunction (3) Patients with pacemakers, intracranial metal implants, or cranial defects (4) Patients with a history of epilepsy, a history of idiopathic epilepsy in a first-degree relative, and use of epileptogenic drugs (5) Patients who have not received treatment for more than three days (6) Refusal to sign an informed consent form. (7) Patients who have participated in other related studies.

Design outcomes

Primary

MeasureTime frame
Functional Near Infrared Spectroscopy;Surface Electromyography;

Secondary

MeasureTime frame
Fugl-Meyer upper limb Scale;Modified Barthel index;

Countries

China

Contacts

Public ContactLei Dai

Zhejiang University of Traditional Chinese Medicine

2406780083@qq.com15156001276

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026