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Study of contralateral C7 nerve transfer to C5 plus C7 in the treatment of central hemiplegia

Study of contralateral C7 nerve transfer to C5 plus C7 in the treatment of central hemiplegia

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200066681
Enrollment
Unknown
Registered
2022-12-13
Start date
2022-12-30
Completion date
Unknown
Last updated
2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

upperlimb hemiplegia after central nervous system injury

Interventions

surgery group:CC7-C5C7

Sponsors

Jing'an District Central Hospital, Fudan University, Shanghai
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: a. Spastic hemiplegia of unilateral upper limb caused by cerebral hemorrhage, stroke, brain injury, encephalitis, cerebral palsy and other reasons; Age: 18-65 years old, male and female. b. The muscle strength of shoulder joint before operation was M0-M1, including shoulder abduction, shoulder flexion and extension. Shoulder spasm was rated 0-1 on the modified Ashworth scale; X-ray showed shoulder dislocation. d. After at least one year of rehabilitation training, the functional recovery of upper limbs has entered the platform stage with no more improvement. e. Preoperative evaluation confirmed that the function of the contralesional cortex was normal

Exclusion criteria

Exclusion criteria: 1) serious systemic diseases, such as hypertension, heart disease symptoms, diabetes, undiagnosed liver disease or disorder (based on serum liver enzyme test results), kidney disease or renal dysfunction, severe anemia, history of deep vein thrombosis, pulmonary artery embolism or cerebrovascular accident, cancer; 2) Patients who cannot take care of themselves, such as unable to walk independently; 3) Recurrence of acute hemorrhage or infarction; 4) The dislocation of shoulder joint caused by pripheral nerve/ tendon/ muscle injury and joint abnormality was excluded. 5) Severe contracture or joint deformity; 6) The patient suffers from severe and untreated neuropsychiatric disorders and cannot communicate normally;

Design outcomes

Primary

MeasureTime frame
Fugl-Meyer scale, MAS scale;

Countries

China

Contacts

Public ContactWendong Xu

Jing'an District Central Hospital

wendongxu@fudan.edu.cn+86 21 52888732

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026