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Clinical observation of gene-directed personalized medication in patients with hypertension

clinical medicine

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2200066668
Enrollment
Unknown
Registered
2022-12-13
Start date
2022-12-20
Completion date
Unknown
Last updated
2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypertension

Interventions

Gene-directed anti-hypertensive drug selection group (observation group):Genetically directed selection of antihypertensive drugs
Evidence-based medicine directed selection of anti-hypertensive drugs (control group):Evidence-based medicine directed selection of anti-hypertensive drugs

Sponsors

Liaoning province Benxi Central Hospital/ Liaoning province Benxi Clinical Biobank
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: (1) age >18 years old, regardless of gender; (2) essential hypertension; According to the blood pressure measurement method in the Chinese Guidelines for the prevention and treatment of hypertension (2018 revision), SBP and/or DBP in sitting position were =140mmHg and/or =90 mmHg for three consecutive different days.

Exclusion criteria

Exclusion criteria: (1) secondary hypertension; (2) within 3 months after the onset of an acute cardio-cerebrovascular event; (3) patients with severe cardiomyopathy, rheumatic heart disease, congenital heart disease, and severe liver and kidney diseases.

Design outcomes

Primary

MeasureTime frame
Hypertension control rate (<130/80mmHg);

Secondary

MeasureTime frame
Degree of change in mean systolic and diastolic blood pressure;

Countries

China

Contacts

Public ContactHui He

Liaoning province Benxi Central Hospital/ Liaoning province Benxi Clinical Biobank

lnbxwxf@yeah.net18941435621

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026