Early predictors and biomarkers of chronic critical illness after sepsis

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2200066657

Enrollment

Unknown

Registered

2022-12-13

Start date

2022-12-01

Completion date

Unknown

Last updated

2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

sepsis,chronic critical illness

Interventions

CCI group:N/A

Non CCI group:N/A

Early death group:N/A

Eligibility

Sex/Gender

All

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: ? Over the age of 18; ? It meets the definition of sepsis 3.0; ? The informed consent has been signed.

Exclusion criteria

Exclusion criteria: ? non-sepsis cases; ? Refractory shock (death within 24 hours) or the source of infection cannot be eliminated; ? Advanced tumor; ? Cases that refused active rescue; ? Long-term use of hormone or immunosuppressive therapy, including the application of anti-rejection drugs after organ transplantation; ? Severe craniocerebral trauma (based on craniocerebral CT); 8 points); ? Pregnant or lactating women; ? Patients receiving radiotherapy and chemotherapy within 30 days; ?HIV infection; ? Serious cardiovascular and cerebrovascular events and other factors that require long-term life support.

Design outcomes

Primary

Measure	Time frame
Charlson comorbidity index;FRAIL Infirmity Scale;IL-6;IL-10;	—

Secondary

Measure	Time frame
high-sensitivity C-reactive protein;Plasma amyloid protein;	—

Countries

China

Contacts

Public ContactXiaolong She

Shenzhen Longgang District People's Hospital

sxlong09@126.com18823846983

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026