gynaecological day surgery
Conditions
Interventions
control group:Giving 0 ug/kg alfentanil before giving remimazolam and 20 ug/kg alfentanil after falling asleep
Observation group 1:Giving 5ug/kg alfentanil before giving remimazolam and 15ug/kg alfentanil after sleeping
Observation group 2:Giving 10ug/kg alfentanil before giving remimazolam and 10ug/kg alfentanil after sleeping
Observation group 3:Giving 20ug/kg alfentanil before giving remimazolam and 0ug/kg alfentanil after sleeping
Sponsors
Weifang people's Hospital
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: ? Day surgery patients who receive gynecological hysteroscopy or conization at a selected time; ? ASA ? - ? patients; ? Age 18-65; ? BMI 18.5~28
Exclusion criteria
Exclusion criteria: 1) Patients with psychosocial diseases and nervous system diseases 2) Patients who take antipsychotic drugs such as tranquilizer and antianxiety, and who drink or abuse drugs 3) Patients with language communication, vision or hearing impairment 4) Hypertension patients whose blood pressure was not controlled satisfactorily after antihypertensive drug treatment (sitting systolic blood pressure = 160mmHg, and/or diastolic blood pressure = 100mmHg in screening period) 5) SBP2, basic SpO2<92%); 8) Severe liver function damage; 9) Severe renal function damage; 10) Allergies to or contraindications to benzodiazepines, propofol, and their drug components; 11) Participated in clinical trials of Remazolam or other drugs as a subject in recent 3 months;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Induction dose of remimazolam; | — |
Secondary
| Measure | Time frame |
|---|---|
| Hemodynamic indexes;Adverse reactions during induction;AI anesthesia depth monitoring;Time of falling asleep, time of anesthesia and time of awakening;Postoperative adverse reactions; | — |
Countries
China
Contacts
Public ContactJi Fanceng
Weifang people's Hospital
Outcome results
None listed