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Discovery of DNA methylation markers in peripheral blood mononuclear cells, innovation of detection technology and application value in early diagnosis of malignant tumors

Discovery of DNA methylation markers in peripheral blood mononuclear cells, innovation of detection technology and application value in early diagnosis of malignant tumors

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2200066626
Enrollment
Unknown
Registered
2022-12-12
Start date
2020-05-01
Completion date
Unknown
Last updated
2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Breast cancer, colorectal cancer, lung cancer

Interventions

Sponsors

The Second Hospital of Shandong University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
30 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Malignant tumor group: Inclusion criteria: - Men and women aged from 30 to 80 years old; - The examination results within the last six months met the diagnostic criteria for malignant tumors as specified in this study 2. Benign disease or healthy group: Inclusion criteria: - Men and women aged from 30 to 80 years old; - Examination results within the last six months met the diagnostic criteria for benign disease or health as specified in this study

Exclusion criteria

Exclusion criteria: 1. Malignant tumor group: Exclusion criteria: -Patients with previous findings suggestive of immune disorders due to other causes. -Diagnosed as malignant tumor before or during hospitalization -Patients with more than two tumors -Patients who have received allogeneic blood transfusion or cell therapy within 1 year. -Pregnant females. 2. Benign disease or healthy group: Exclusion criteria: - Patients with previous findings suggestive of immune disorders due to other causes. - Patients who have received allogeneic blood transfusion or cell therapy within 1 year. - Pregnant females.

Design outcomes

Primary

MeasureTime frame
DNA methylation sites;

Countries

China

Contacts

Public ContactChuanxin Wang

The Second Hospital of Shandong University

cxwang@sdu.edu.cn18560083188

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026