To explore the influence mechanism of different types of exercise on cognitive brain function in patients with Mild Cognitive Impairment

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2200066625

Enrollment

Unknown

Registered

2022-12-12

Start date

2022-12-15

Completion date

Unknown

Last updated

2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mild Cognitive Impairment

Interventions

Resistance stretching exercise task group:Use a multi-function chest expandable stretcher to perform resistance stretching exercises (3 minutes per session, 3 sessions in total, 12 minutes in total)

Aerobic game exercise task group:Perform the dance game movement task (3 minutes per session, 3 sessions in total, 12 minutes in total)

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1.50= age =65; 2.The right handedness was evaluated by the Edinburgh Handedness Inventory; 3.Mild Cognitive Impairment with the Montreal Cognitive Assessment (MoCA) score of 18-26; 4.Electrocardiogram has no obvious factors interfering with the study; 5.Have the ability to perform sports; 6.The informed consent has been signed.

Exclusion criteria

Exclusion criteria: 1.Have long-term alcohol abuse or long-term use of diuretics, sedatives, antidepressants, antiepileptic drugs and other drugs that will affect cognitive function; 2.Diagnosed with a neurodegenerative disease (e.g. Alzheimer's disease); 3.Presence of severe cardiovascular disease (such as cardiac or respiratory insufficiency); 4.Presence of musculoskeletal disorders with imbalance and gait disturbance; 5.Use walking AIDS (e.g., crutches); 6.Severe visual/hearing/movement disorders; 7.Any other factors that may hinder the full and safe participation of the subjects in exercise and/or cognitive training; 8.Termination of cooperation due to increased blood pressure than expected during exercise or persistent fever or persistent body pain for other reasons; 9.Pregnancy.

Design outcomes

Primary

Measure	Time frame
Functional near-infrared spectroscopy;Modified facial 2-back paradigm;	—

Secondary

Measure	Time frame
Heart rate;Blood pressure;Changes in oxygen saturation;G-Walk reverse digits recall the number of correct responses;stride frequency;Walk pace;Step length;	—

Countries

China

Contacts

Public ContactLin Qiang

The fifth affiliated Hospital of Guangzhou Medical University

qianglin0925@gzhmu.edu.cn+86 18922497674

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026