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Effect of Gronium bromide injection on preventing nausea and vomiting in gynecological laparoscopic surgery

Effect of Gronium bromide injection on preventing nausea and vomiting in gynecological laparoscopic surgery

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200066599
Enrollment
Unknown
Registered
2022-12-11
Start date
2022-12-01
Completion date
Unknown
Last updated
2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anesthesiology and ponv

Interventions

Gelomonium Bromide:Gelomonium and Tropisetron

Sponsors

jiang Hospital Affiliated to Chongqing University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1.18 years = age :70 years: 2. The patient's ASA score was 1-111 3. Determine the need for gynecological laparoscopic surgery under general anesthesia: 4. Patients who voluntarily received postoperative self-controlled intravenous analgesia: 5. Willing to participate in the study and sign the informed consent.

Exclusion criteria

Exclusion criteria: 1. History of mental illness or use of psychotropic drugs for treatment: 2. A history of drug, alcohol or opioid abuse; 3. Taking other experimental drugs or participating in other clinical trials 3 months before study inclusion: 4. Patients with severe dysfunction of the heart, brain, liver, kidney and hematopoietic system: 5. Arrhythmias (including bradycardia, ventricular tachycardia, prolonged ventricular frontal and QTc intervals, etc.): 6. Glaucoma patients 7. Myasthenia gravis patients 8. Patients with paralytic intestinal obstruction, pyloric stricture and prostatic hypertrophy: 9. Patients with hyperthyroidism 10. Patients with epilepsy 11. Patients with other contraindications to gronammonium bromide or toanisetron: 12. Allergic constitution and allergy to anticholinergic drugs: 13. Failure to cooperate with the study for any reason.

Design outcomes

Primary

MeasureTime frame
Nausea score/frequency of vomiting;

Countries

China

Contacts

Public ContactLiwen Fan

Qianjiang Hospital Affiliated to Chongqing University

415316943@qq.com13452235951

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026