Effect of different doses of esketamine combined with propofol and sufentanil on intraocular pressure during general anesthesia induction period in pediatric strabismus surgery

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2200066586

Enrollment

Unknown

Registered

2022-12-09

Start date

2022-12-30

Completion date

Unknown

Last updated

2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anesthesia for strabismus surgery

Interventions

Normal saline group:induction by Propofol+sufentanil+normal saline

Esketamine 0.25mg/Kg group:induction by Propofol+sufentanil+esketamine 0.25mg/Kg

esketamine 0.5mg/Kg group:induction by Propofol+sufentanil+esketamine 0.5mg/Kg

Eligibility

Sex/Gender

All

Age

7 Years to 13 Years

Inclusion criteria

Inclusion criteria: ? ASA grade I - II; ? Age 7-12 years; ? Children undergoing strabismus surgery under general anesthesia; ? The family members of the child are informed and sign the informed consent form

Exclusion criteria

Exclusion criteria: ? Children with glaucoma, keratopathy, retinopathy and neuromuscular disease history, upper respiratory tract infection or difficult airway within two weeks before operation; ? Children with allergy to drugs that affect intraocular pressure, related general anesthesia and local anesthetic drugs used within 2 days before operation; ? Children unable to measure intraocular pressure under topical anesthesia before anesthesia

Design outcomes

Primary

Measure	Time frame
introcular pressure;	—

Secondary

Measure	Time frame
blood pressure;heart rate;	—

Countries

China

Contacts

Public ContactLuo jun

Tianjin Eye Hospital

jeff_8225@163.com+86 18602630086

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 8, 2026