Prostate Cancer
Conditions
Interventions
Gold Standard:The criteria for staging are based on post-operative pathology or follow-up results
biochemical efficiency assessment criteria: (1) complete response (CR): PSA = 0ng/mL
(2) partial response (PR): ?PSA (?PSA = (PSA2-PSA1)/ PSA1 x 100) % = -50%
(3) stable disease (SD): ?PSA of -49% ~ +24%
(4) progressive
Index test:Dual-tracer PET/CT with 18F-FDG and 68Ga-PSMA
Sponsors
West China Hospital of Sichuan University
Eligibility
Sex/Gender
Male
Inclusion criteria
Inclusion criteria: 1. General information is available, such as age, treatment history, PSA levels, Gleason score, etc.; 2. Age>18 years; 3. Pathologically confirmed prostate cancer; 4. Patients with primary high-risk prostate cancer:(1)T-stage>3a,(2)PSA >20 ng/ml,(3)Gleason score>8 (at least 1 of these criteria is met); or patients with recurrent prostate cancer: (1)initial Gleason score>8,(2)diagnosed as CRPC with biochemical recurrence,(3)a PSA level >0.2 ng/mL; 5. KPS score=50.
Exclusion criteria
Exclusion criteria: 1.Patients with other tumor histories; 2.Patients with claustrophobia; 3.Patients with blood glucose levels> 8.1mmol/L.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sensitivity;Specificity;Accuracy;Efficacy evaluation; | — |
Countries
China
Contacts
Public ContactMinggang Su
West China Hospital of Sichuan University
Outcome results
None listed