gallstones
Conditions
Interventions
Prospective longitudinal study group:None
Sponsors
West China Hospital of Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1.Patients aged 18-65 years; 2.Patients diagnosed with gallstones by ultrasound and proposed for laparoscopic cholecystectomy; 3.Patients residing in Chengdu urban area; 4.Patients who gave informed consent to this study and voluntarily participate.
Exclusion criteria
Exclusion criteria: 1.previous history of gastrointestinal surgery;2.history of irritable bowel syndrome, inflammatory bowel disease, constipation, chronic diarrhea, infectious or idiopathic diarrhea and patients with severe heart, liver, kidney disease or malignant disease;3.combined with other metabolic diseases (diabetes, gout, metabolic syndrome, etc.) and infectious diseases; 4.use of antibiotics, probiotics, prebiotics, laxatives or other drugs known to affect the intestinal flora within the last 3 months;5.Patients undergoing emergency surgery; 5.Patients with residual stones, bile duct injury, bile duct stricture after laparoscopic cholecystectomy; 6.Pregnant or lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Bristol stool classification;Diversity of gut microbiota;Gut micobiota abundance;Gut microbiota gene function; | — |
Secondary
| Measure | Time frame |
|---|---|
| Diet frequency score;Blood cell classification;Biochemical index; | — |
Countries
China
Contacts
Public ContactLi Ka
West China School of Nursing /West China Hospital, Sichuan University
Outcome results
None listed