migraine
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: ? Patients who meet the diagnostic criteria, and no abnormality is found through head CT or MRI; ? 18 = 60 years old, and the age of first onset is less than 50 years old; ? At least 2 attacks per month, less than 15 days of headache per month, and migraine history = 1 year; ? The patient or his family members agree to sign the informed consent form.
Exclusion criteria
Exclusion criteria: ?Headache is caused by other diseases (such as hypertension, epilepsy, etc.) ?Pregnant or lactating women ?Patients with serious primary diseases such as cardiovascular, urinary, digestive and blood systems ?Patients with cognitive impairment, aphasia, dyslexia and other symptoms ?Patients unable to cooperate with treatment or fill in the scale correctly ?Alcohol or drug abusers
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Definition of migraine day;Definition of moderate/severe headache day; | — |
Secondary
| Measure | Time frame |
|---|---|
| Definition of responder rate;Headache severity;PHQ-9;GAD-7;PSQI;HIT-6;Cerebral hemodynamic indicators;MSQ; | — |
Countries
China
Contacts
The First Affiliated Hospital of Heilongjiang University of Chinese Medicine