Emergence agitation in children
Conditions
Interventions
Dexmedetomidine group:Dextrmedetomidine 1ug/kg intravenous infusion
Esketamine group:Esketamine 0.3mg/kg intravenously
Sponsors
The First Affiliated Hospital of Guangxi Medical University
Eligibility
Sex/Gender
All
Age
1 Years to 7 Years
Inclusion criteria
Inclusion criteria: 1. ASA I or II; 2. Children aged from 1 to 7 years who need laparoscopic surgery for endotracheal intubation and general anesthesia; 3. There was no obvious disease of heart, liver, kidney or nervous system before operation.
Exclusion criteria
Exclusion criteria: 1. Allergic to dexmedetomidine, esketamine and other drugs; 2. Children with congenital heart disease, asthma, mental diseases and other diseases; 3. History of respiratory tract infection 1 week before surgery; 4. Preoperative liver and/or renal dysfunction; 5. Long-term use of sedative or analgesic drugs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 5-point Agitation Scale;Face, Legs, Activity, Crying, Consolability Score for pain;Pediatric Anesthesia Emergence Delirium Scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| Heart rate;Mean arterial pressure;Pulse oxygen saturation; | — |
Countries
China
Contacts
Public ContactLin Yu'nan
The First Affiliated Hospital of Guangxi Medical University
Outcome results
None listed