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Prospective cohort trial of long-term efficacy of balloon dilation versus stenting in symptomatic middle cerebral artery stenosis

Prospective cohort trial of long-term efficacy of balloon dilation versus stenting in symptomatic middle cerebral artery stenosis

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200066523
Enrollment
Unknown
Registered
2022-12-07
Start date
2022-12-20
Completion date
Unknown
Last updated
2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cerebrovascular disease

Interventions

Experimental group:Interventional balloon dilatation
Control group:Interventional stent implantation

Sponsors

Shenzhen Second People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
45 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Aged between 45 and 75 years (including 45 and 75); 2. Definite decline in language/physical activity/feeling or analytical thinking (e.g. headache, dizziness, weakness of one limb, speech fluency, cognitive decline, etc.); 3. Craniocerebral CTA/MRA/DSA examination indicated craniocerebral middle cerebral artery stenosis (and stenosis degree >=70%); 4. No history of new cerebral infarction in recent half a year; 5. Patients without serious underlying diseases such as heart valvular disease, malignant tumor and cachexia; 6. Signed informed consent for surgery and informed consent for research.

Exclusion criteria

Exclusion criteria: 1. When it is found that the middle cerebral artery stenosis site is long segment, fine terminal branch or severely curved site, there is no alternative treatment; 2. A long history of primary migraine; 3. Patients with hemiplegia and decreased muscle strength in one limb in recent half a year; 4. Pregnant patients.

Design outcomes

Primary

MeasureTime frame
Degree of stenosis;

Secondary

MeasureTime frame
Patient cognitive function score;

Countries

China

Contacts

Public ContactGong Songfeng

Shenzhen Second People's Hospital

gsf1412@163.com+86 18922873965

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026