Congenital heart disease
Conditions
Interventions
Experimental group:para vertebral block
Control group:conventional fast track anesthesia
Sponsors
Fuwai Yunnan Cardiovascular Hospital
Eligibility
Sex/Gender
All
Age
1 Years to 6 Years
Inclusion criteria
Inclusion criteria: 1. Children aged from 1 to 6 years; 2. Cardiopulmonary bypass repair of atrial septal defect and/or ventricular septal defect with right chest wall incision in left decubitus position; 3. Informed consent signed by the child's parents or legal guardians.
Exclusion criteria
Exclusion criteria: 1. Preoperative intravenous use of positive inotropic drugs, tracheal intubation or mechanical circulation AIDS; 2. Emergency surgery or secondary heart surgery; 3. Weight of children 30kg; 4. The patient was diagnosed with severe pulmonary hypertension after preoperative evaluation; 5. The last preoperative echocardiography showed that the left ventricular ejection fraction was less than 45%; 6. The child was allergic to ropivacaine or drugs routinely used during and after surgery; 7. Preoperative platelet count was lower than 100x10^9/L or coagulation function was abnormal (PT was longer than the normal high value for 3s; INR>1.5; APTT more than 10s longer than the normal high value); Or the child has a bleeding tendency (including gingival bleeding, skin ecchymosis, poor blood coagulation by venipuncture, etc.); 8. Preoperative use of antiplatelet drugs or anticoagulant drugs; 9. Contraindications of spinal deformity or other paravertebral block in the patient.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the opioids consumption within 24 hours after operation; | — |
Secondary
| Measure | Time frame |
|---|---|
| FLACC Scale Score;The rate of opioid treatment for remedial analgesia between groups;The first time of FLACC>=4 after end of surgery;The incidence of excessive hemodynamic fluctuation after incising in both groups;Serum concentration of inflammation factors (IL-6, IL-8, IL-10);Stress hormones (cortisol, epinephrine and norepinephrine);The rate of postoperative nausea and vomiting (PONV) during the 24h after end of surgery;The incidence of respiratory depression;Length of endotracheal intubation;Length of postoperative ICU stay;Length of postoperative hospital stay; | — |
Countries
China
Contacts
Public ContactJia Yuan
Fuwai Yunnan Cardiovascular Hospital
Outcome results
None listed