Prospective, comparative, and interventional study on vitrectomy for non-arteritic anterior ischemic optic neuropathy

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2200066515

Enrollment

Unknown

Registered

2022-12-07

Start date

2022-09-22

Completion date

Unknown

Last updated

2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Non-arteritic anterior ischemic optic neuropathy (NAION)

Interventions

Experimental group:pars plana vitrectomy

Control group:conventional medical treatment

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Patients with typical symptoms and signs of NAION, including acute visual loss, relative afferent pupil defect, optic disc swelling, blurred optic disc margins with or without bleeding, and characterized visual field defects consistent with optic neuropathy. 2. NAION patients with incomplete papillary vitreous detachment and peripapillary wrinkles. 3. Patients with NAION presenting with optic disc edema within 2 months of onset.

Exclusion criteria

Exclusion criteria: 1. Inflammatory, hereditary, traumatic and other causes of optic nerve diseases. 2. Retinopathy, such as high myopia retinopathy, proliferative diabetic retinopathy. 3. History of any previous eye disease, internal eye surgery and laser photocoagulation therapy. 4. Obvious turbidity of the refractive medium.

Design outcomes

Primary

Measure	Time frame
visual field inspection;best corrected visual acuity;swept source optical coherence tomography;	—

Countries

China

Contacts

Public ContactLi Xiaorong

Tianjin Medical University Eye Hospital

xiaorli@163.com+86 18622818042

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026