MRKH syndrome
Conditions
Interventions
Dilation group:Vaginal dilation
Sponsors
Chinese Academy of Medical Sciences & Peking Union Medical College
Eligibility
Sex/Gender
Female
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: Patients may choose to enter the cohort when they meet all of the following criteria: 1) Normal female karyotype (46, XX); 2) Pelvic ultrasound or MRI diagnoses all or part of the primordial uterus and vagina; 3) After informing the patient of the dilation method and surgical vaginoplasty information, voluntarily choose the dilation method; 4) Age >= 18 years old; 5) Agree to participate in this research.
Exclusion criteria
Exclusion criteria: When a patient has any of the following conditions, she cannot be selected for clinical research: 1) Abnormal karyotype, such as 45,X0 or male karyotype (46,XY; 47,XXY; 47,XYY, etc.) 2) Those who require surgery or surgical vaginoplasty for vaginal narrowing; 3) Refusal to participate in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The length of vagina;FSFI; | — |
Secondary
| Measure | Time frame |
|---|---|
| SF-12;PHQ-9, GAD-7; | — |
Countries
China
Contacts
Public ContactLan Zhu
Chinese Academy of Medical Sciences & Peking Union Medical College
Outcome results
None listed