inflammatory bowel disease
Conditions
Interventions
IBD Patients in Sichuan Province:No
Health Control in Sichuan Province:No
IBD Patients in Xinjiang Autonomous Region:NO
Health Control in Xinjiang Autonomous Region:No
Sponsors
West China Hospital, Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1.Inclusion criteria for IBD patients: clinically confirmed IBD patients who had not used antibiotics or probiotics in the past 1 month. 2.Inclusion criteria for healthy controls: healthy volunteers, without autoimmune diseases (such as celiac disease, arthritis, multiple sclerosis, connective tissue disease, psoriasis), chronic diseases (such as liver cirrhosis, diabetes, hypertension, coronary heart disease, asthma, chronic obstructive pulmonary disease, etc.), and without any drug use in 1 month. No history of infectious diseases (such as hepatitis, syphilis, HIV, tuberculosis, malaria, schistosomiasis, etc.) or sojourn in infectious diseases area; No acute or chronic intestinal diseases (such as acute and chronic enteritis, functional bowel disease, inflammatory bowel disease, intestinal polyps or malignant tumors); No blood transfusion; No history of drug use; Regular defecation, shape, smooth.
Exclusion criteria
Exclusion criteria: 1. Exclusion criteria for IBD patients: exclusion criteria were patients with infectious diseases, tumors, liver cirrhosis, heart failure, respiratory failure, and renal failure. 2.Exclusion criteria for healthy controls: volunteers who met the inclusion criteria were excluded from the study if they had any of the following: atopic diseases (such as allergic rhinitis, allergic asthma, atopic dermatitis, etc.); Mental disorders such as depression and anxiety; Diseases requiring maintenance medication; Diseases of the nervous system or neurodegeneration; History of gastrointestinal surgery (except appendectomy); Family history (siblings and parents) of Crohn's disease, ulcerative colitis, celiac disease, colorectal cancer, polyposis, diabetes, psychiatric disorders, and other genetic diseases; Gastrointestinal discomfort in the last month: such as any moderate-to-severe upper gastrointestinal discomfort, diarrhoea, constipation, moderate-to-severe abdominal distension, moderate-to-severe nausea, painful bowel movements, mucus in stools, blood in stools, or any blood signs related to bowel movements; He had a history of catharsis and intestinal lavage cosmetology in the past 3 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| difference of dietary pattern or composition; | — |
Secondary
| Measure | Time frame |
|---|---|
| intestinal microbiota;metabolite; | — |
Countries
China
Contacts
Public ContactLei Shi
West China Hospital, Sichuan University
Outcome results
None listed