dry eye
Conditions
Interventions
Experimental group:The experimental group was treated with 0.05% cyclosporine eye drops bid combined with calf blood eye drops qid
control group:The control group was treated with calf blood eye drops.qid
Healthy control group:N/A
Sponsors
Tianjin Medical University Eye Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. The age is from 18 to 70 years old, male or female. According to the consensus of dry eye experts in 2020, it meets the diagnostic criteria of moderate and severe dry eyes 3. Eyesight of daily life =>= 0.1
Exclusion criteria
Exclusion criteria: (1) highly sensitive to cyclosporine and / or any drug; (2) complicated with diseases other than cataract that affect vision, such as glaucoma, diabetic retinopathy, retinal detachment, etc. (3) immunosuppressants other than cyclosporine are being used or treated. (4) severe primary diseases and malignant tumors such as heart, cerebrovascular, liver and kidney, endocrine and hematopoietic system; (5) history of drug use, drug abuse or malignant tumor; (6) severe, recurrent and chronic infection after or recently after organ transplantation, including HIV, hepatitis, tuberculosis, syphilis, etc.; (7) women of pregnancy, lactation or planned pregnancy age. 8 use of corneal contact lenses or current or recent use of lacrimal plugs; 9 plans for eye surgery during recent eye surgery or research.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Confocal corneal microscope;Eye surface analysis;Imprinted conjunctival cell; | — |
Secondary
| Measure | Time frame |
|---|---|
| intraocular pressure; | — |
Countries
china
Contacts
Public ContactRuihua Wei
Tianjin Medical University Eye Hospital
Outcome results
None listed