Efficacy and safety of mood stabilizers versus antidepressants for youth depression: a randomised, open-label, pilot study

Efficacy and safety of medicine treatment for youth depression

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2200066412

Enrollment

Unknown

Registered

2022-12-05

Start date

2022-12-01

Completion date

Unknown

Last updated

2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Depression

Interventions

mood stabilizers:Lamotrigine and Lithium Carbonate Sustained-release

antidepressants:Sertraline

Eligibility

Sex/Gender

All

Age

12 Years to 17 Years

Inclusion criteria

Inclusion criteria: 1. Men and women, aged 12 to 17 years 2. DSM-5 diagnosis of major depression disorder

Exclusion criteria

Exclusion criteria: 1. Having other mental illness 2. Treatment with psychotropic medication in 2 weeks, unstable medical conditions. 3. those having serious medical illnesses 4. pregnancy

Design outcomes

Primary

Measure	Time frame
HAMD;	—

Secondary

Measure	Time frame
HAMA;CGI;NSSI;SOFAS;Stroop test;SDMT;	—

Countries

China

Contacts

Public ContactGang Wang

Wuhan Mental Health Center

532614206@qq.com+86 18162708527

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026