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Assessment of Left Atrial Strain by ultrasound combined with Electro anatomical mapping study to predict clinical outcomes after radiofrequency ablation surgery in patients with paroxysmal atrial fibrillation (LASEAMAF) Study

Assessment of Left Atrial Strain by ultrasound combined with Electro anatomical mapping study to predict clinical outcomes after radiofrequency ablation surgery in patients with paroxysmal atrial fibrillation (LASEAMAF) Study

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2200066408
Enrollment
Unknown
Registered
2022-12-05
Start date
2022-08-18
Completion date
Unknown
Last updated
2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

atrial fibrillation

Interventions

radiofrequency ablation group:No

Sponsors

Guangdong Cardiovascular Institute, Guangdong Provincial People’s Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: (1) Patients with a diagnosis of paroxysmal atrial fibrillation. (2) Eligible for catheter-based radiofrequency ablation procedure treatment and undergoing ablation for the first time. (3) Male or non-pregnant female aged 18-80 years; completed transesophageal echocardiography with a left ear emptying velocity >40 cm/s measured by pulsed Doppler and who voluntarily participated in the study and signed consent form.

Exclusion criteria

Exclusion criteria: 1) Patients with severe hepatic or renal insufficiency with glutathione/glutathione transaminase exceeding the upper limit of normal by more than 3 times; eGFR 50 mm in parasternal long-axis view or LVEF 100s, allergy, active bleeding, previous history of intracranial bleeding, history of gastrointestinal bleeding within 6 months and history of bypass surgery within 30 days) 8) Contraindication to anticoagulants or accepted pacemaker implantation. 9) Participants in clinical trials of any other drug within 1 month prior to surgery and those who refused this study.

Design outcomes

Primary

MeasureTime frame
Atrial fibrillation recorded on an electrocardiogram triggered by routine during the clinic follow up in 1year.;

Secondary

MeasureTime frame
Atrial tachycardia lasting at least 30 seconds was recorded on a routine or symptom-triggered ECG during the clinic;

Countries

China

Contacts

Public ContactQingshan Geng

Guangdong Cardiovascular Institute, Guangdong Provincial People’s Hospital

gengqsh@163.net+86 020 83827812

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026