Cognitive Dysfunction
Conditions
Interventions
Control group:None
Sponsors
Liuzhou People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Meet the indications for laparoscopic partial hepatectomy 2. Age 18-65 years old, gender is not limited 3. BMI 18-30kg/m2 4. ASA class I-III, Child-Pugh score A, no significant other systemic comorbidities
Exclusion criteria
Exclusion criteria: 1. ASA class IV-V, severe cardiopulmonary and cerebral disease, and significant abnormalities in renal function 2. Previous history of depression, schizophrenia, epilepsy, Parkinson's disease, or myasthenia gravis 3. Inability to complete preoperative evaluation due to severe dementia, speech impairment, hearing impairment, coma, end-stage disease, etc. 4. History of previous cranial surgery 5. Preoperative MMSE score <24 6. refused to participate in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| MMSE score at 7 days postoperatively;Postoperative 30-day TICS-M score;MMSE score 30 days after surgery;Sleeping time 7 day after surgery;Number of awakenings 7 day after surgery;7-day postoperative PSQI score;LSEQ score 7 days after surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| PSQI score 1 day before surgery;LSEQ score 1 day before surgery;Sleeping time 1 day after surgery;Number of awakenings 1 day after surgery;PSQI score 1 day after surgery;LSEQ score 1 day after surgery; | — |
Countries
china
Contacts
Public Contactmin liu
Department of Anesthesiology, Liuzhou People's Hospital
Outcome results
None listed