Volume management of pregnant women with twin pregnancy
Conditions
Interventions
Group H(11%=SVV=15%):N/A
Group L(6%=SVV=10%):N/A
Sponsors
Nanjing Maternal and Child Health Hospital
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: American Society of Anesthesiologists score (American Society of Anesthesiologists,ASA) is I~II, elective twin pregnancy cesarean section, age 18 to 45 years old.
Exclusion criteria
Exclusion criteria: 1, twin pregnant women with vaginal trial delivery, 2, pregnant women with cardiopulmonary, hepatorenal insufficiency, 3, pregnant women with severe infection, dehydration, electrolyte disturbance and shock, 4, parturients with abnormal blood coagulation and moderate and severe anemia, 5. History of hypersensitivity to hydroxyethyl starch HES (130ram0.4) and sodium lactate Ringer injection (SodiumLactateRinger'sInjection,LR). 6. application of drugs that affect cardiac function, such as ß-receptor antagonists, calcium channel blockers, digitalis, etc.; 7, severe brain injury, confusion of consciousness, respiratory inhibition; 8, absolute contraindications of intraspinal anesthesia; 9. Parturients who have participated in other clinical trials and are participating in other clinical trials within 3 months before joining the group. 10. According to the doctor in charge of the trial, the implementation of the trial may increase the risk of the subjects, or may not be able to obtain sufficient trial data.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| diamine oxidase, DAO;N terminal pro B type natriuretic peptide, NT-proBNP; | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative quality of recovery score, QoR-40;Neonatal outcome; | — |
Countries
China
Contacts
Public ContactHuiying Zhang
Nanjing Maternal and Child Health Hospital
Outcome results
None listed