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Characteristics of monocytes, macrophages and T cells in peripheral blood leukocytes of patients with acute coronary syndrome and their influence on the incidence of MACE after 1 year

Characteristics of monocytes, macrophages and T cells in peripheral blood leukocytes of patients with acute coronary syndrome and their influence on the incidence of MACE after 1 year

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2200066382
Enrollment
Unknown
Registered
2022-12-03
Start date
2022-12-03
Completion date
Unknown
Last updated
2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute coronary syndrome

Interventions

control group:None

Sponsors

The Affiliated Hospital of Guizhou Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 100 Years

Inclusion criteria

Inclusion criteria: 1. In accordance with the guidelines for definite diagnosis of ACS and in patients undergoing PCI treatment: patients with acute myocardial infarction (including st-elevation myocardial infarction and non ST segment elevation myocardial infarction) diagnostic criteria: typical chest pain lasts more than 30 min, a typical dynamic electrocardiogram (ecg) changes or myocardial enzyme (creatine kinase isozyme or troponin) dynamic evolution;The diagnosis criteria of unstable angina(UA) is that history(risk factors for coronary heart disease), symptoms(initial or aggravation angina pectoris in 1 month), and ECG showing that ST-segment depresses or T wave changes. 2. Onset time =2 weeks; 3. Age range of included patients: 18-100 years old; 4. The subjects are willing to comply with the trial protocol, can understand the purpose of the trial, voluntarily participate in the trial or their legal guardian and sign the informed consent form, aged =18 years; 5. Complete clinical data and real follow-up data.

Exclusion criteria

Exclusion criteria: 1. Incomplete clinical data or (and) questionable authenticity of follow-up data; 2. Patients with dilated cardiomyopathy, hypertrophic cardiomyopathy, severe cardiogenic shock, history of active endocarditis, rheumatic heart disease, or severe valvular disease, severe liver and renal dysfunction, Severe hemorrhagic diseases, severe infectious diseases, severe respiratory diseases, hematological diseases, autoimmune diseases and craniocerebral diseases, malignant tumors, pulmonary embolism, ventricular septal perforation and aortic dissection; 3. Subjects who are considered by the investigator to have a serious medical condition that is not suitable for participation in the trial, or who have a life expectancy of less than 12 months; 4. Participating in other clinical trials, not yet out of the group or less than 3 months out of the group; 5. Known hypersensitivity to contrast media; 6. Subjects with contraindications of antiplatelet preparations and unable to receive antithrombotic therapy; 7. The researchers judged that the patients had poor treatment compliance and could not take the drugs for secondary prevention of coronary heart disease regularly as required.

Design outcomes

Primary

MeasureTime frame
Major Adverse Cardiovascular Events;

Secondary

MeasureTime frame
No reflow and atrial fibrillation after PCI, all-cause death other than cardiovascular death, stroke/cerebrovascular accident.;

Countries

China

Contacts

Public ContactLi Wei

The Affiliated Hospital of Guizhou Medical University

liwei249188@sina.com13809482491

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 11, 2026