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A prospective randomized controlled clinical trial of the effect of dexamethasone on perioperative period in patients undergoing hepatectomy with 25 minute intermittent interruption of hepatic blood flow

A prospective randomized controlled clinical trial of the effect of dexamethasone on perioperative period in patients undergoing hepatectomy with 25 minute intermittent interruption of hepatic blood flow

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200066381
Enrollment
Unknown
Registered
2022-12-03
Start date
2022-12-03
Completion date
Unknown
Last updated
2023-06-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

hepatocellular carcinoma

Interventions

Dexamethasone use group:dexamethasone
non use group :N/A

Sponsors

West China Hospital, Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Patients with definite preoperative diagnosis who were selected for hepatectomy; No extrahepatic metastasis was found by preoperative imaging examination; Liver function Child Pugh grade A and B; Understand the trial and sign the patient's informed consent form.

Exclusion criteria

Exclusion criteria: Hepatectomy with other organ operations other than cholecystectomy; The tumor obviously invaded the portal vein or hepatic artery; PVE or TACE surgery was performed in the past. Patients with diabetes. Hepatectomy with other organ operations other than cholecystectomy; The tumor obviously invaded the portal vein or hepatic artery; PVE or TACE surgery was performed in the past. Patients with diabetes.

Design outcomes

Primary

MeasureTime frame
transaminase; under the curve (AUC) of the postoperative course of transaminase.;Peak value of transaminase;

Secondary

MeasureTime frame
total bilirubin;Inflammatory index(PCT/IL-6/CRP);Perioperative complications;blood loss; international normalized ratio;Peak value of total bilirubin;Peak value of inflammatory index;

Countries

China

Contacts

Public ContactLi Jiang
jl339@126.com18980606338

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 9, 2026