Correlation of exosome-miR-124 with chronic brain hypoperfusion

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2200066367

Enrollment

Unknown

Registered

2022-12-02

Start date

2022-12-10

Completion date

Unknown

Last updated

2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chronic brain hypoperfusion

Interventions

CCH:No

Control:No

Eligibility

Sex/Gender

All

Age

40 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1) Chronic cerebral insufficiency, such as dizziness, lightheadedness, headache, cognitive impairment, mood disorders, insidious onset, fluctuating symptoms. 2) Cerebral perfusion imaging (arterial spin labeling, ASL) confirming the presence of cerebral hypoperfusion.

Exclusion criteria

Exclusion criteria: 1) Patients with other neurological and psychiatric disorders that can cause relevant clinical symptoms. 2) Chronic cerebral perfusion insufficiency due to dysthymia, anxiety somatization disorder, depression, AD and various degenerative diseases or subjective dizziness. 3) Patients with autoimmune diseases, tumors, and severe hypertension that cannot be controlled by drugs.

Design outcomes

Primary

Measure	Time frame
microRNA(miR)-124-3p;	—

Countries

China

Contacts

Public ContactNeng-wei Yu

Department of Neurology, Sichuan Provincial People’s Hospital, Chengdu 610072, China.

18981838652@126.com18981838652

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026