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Comparison of anesthetic effects of different doses of alfentanil combined with ciprofol in elderly patients undergoing ERCP

Comparison of anesthetic effects of different doses of alfentanil combined with ciprofol in elderly patients undergoing ERCP

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200066366
Enrollment
Unknown
Registered
2022-12-02
Start date
2022-12-07
Completion date
Unknown
Last updated
2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anesthesia of ERCP

Interventions

A group:Maintenance dose of alfentanil 0.15 µ g/(kg·min)
B group:Maintenance dose of alfentanil 0.25 µ g/(kg·min)
C group:Maintenance dose of alfentanil 0.35 µ g/(kg·min)

Sponsors

Weifang People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
65 Years to 85 Years

Inclusion criteria

Inclusion criteria: ? Elective ERCP operation; ? The age is 65 to 85 years old, regardless of gender; ? The American anesthesiologist association (ASA) is classified as Grade ? to Grade III; ? Body mass index (BMI) is 18-28kg/m2.

Exclusion criteria

Exclusion criteria: Proposed endotracheal intubation (including laryngeal mask airway), serious cardiovascular system disease, severe respiratory disease, long-term history of taking psychotropic drugs and cognitive dysfunction, the modified Malampati rating is Grade IV, history of drug abuse, drug abuse, alcohol abuse, failure to receive regular antihypertensive treatment or poor blood pressure control [SBP = 180 mmHg or = 90 mmHg, and/or DBP = 100mmHg]. ciprofol and other drugs and their components are allergic or contraindicated, and have participated in other clinical trials as subjects in recent 3 months.

Design outcomes

Primary

MeasureTime frame
Respiratory depression;

Secondary

MeasureTime frame
heart rate;mean arterial pressure;Somatic reaction;hypotension;Time of recovery from anesthesia;Operation time;

Countries

China

Contacts

Public ContactHuJun

Weifang People's Hospital of Shandong Province

guyueyinghui@163.com18365679587

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026