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The Impact of Esketamine in Addition to Propofol Sedation on Postoperative Recovery of Ambulatory Colonoscopy

The Impact of Esketamine in Addition to Propofol Sedation on Postoperative Recovery of Ambulatory Colonoscopy: A Randomized Controlled Trial

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200066353
Enrollment
Unknown
Registered
2022-12-02
Start date
2022-12-04
Completion date
Unknown
Last updated
2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Intestinal diseases

Interventions

Esketamine group:Esketamine 0.2mg/kg

Sponsors

Fujian Provincial Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1)Age 18–75 years; 2) American Society of Anesthesiologists (ASA) 1 to 3; 3) Scheduled for ambulatory colonoscopy

Exclusion criteria

Exclusion criteria: 1)Patient refuses to participate; 2) BMI greater than 30; 3) Allergic or contraindication to study drugs; 4) Inability to ambulate without assistance; 5) Required therapeutic endoscopies, such as endoscopic mucosal resection or endoscopic submucosal dissection; 6)History of psychiatric illness; 7)History of neurological disease; 8)History of seizure disorders; 9)History of medication or alcohol abuse 10)Any other conditions that precluded study inclusion, such as cognitive impairment, pregnancy, or inability to communicate in Mandarin Chinese.

Design outcomes

Primary

MeasureTime frame
Recovery in the cognitive domain on postoperative day 3;

Secondary

MeasureTime frame
Postoperative quality of recovery;Emergency time;Propofol consumption;Patient satisfaction;Endoscopist satisfaction;Incidence of adverse events;Sleep quality assessment;

Countries

China

Contacts

Public ContactYusheng Yao

Fujian Provincial Hospital

fjslyys@126.com+86 13559939629

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026