A study of topical oxidative regenerated cellulose in reducing bleeding in total knee replacement patients—a prospective randomized controlled trial

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2200066302

Enrollment

Unknown

Registered

2022-11-30

Start date

2022-12-01

Completion date

Unknown

Last updated

2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Knee arthritis

Interventions

Test group:Topical application of oxidized regenerated cellulose

Control group:Blank control

Eligibility

Sex/Gender

All

Age

50 Years to 80 Years

Inclusion criteria

Inclusion criteria: From December 1, 2022 to March 20, 2023, patients who underwent unilateral primary total knee replacement due to osteoarthritis in Xi'an Red Society Hospital

Exclusion criteria

Exclusion criteria: 1. Preoperative anemia (men 1.4. Activated partial thromboplastin time (APTT) >1.4×normal, platelet <140,000/mm3) 9. Intraoperative complications (fractures, etc.)

Design outcomes

Primary

Measure	Time frame
hemoglobin;	—

Secondary

Measure	Time frame
packed cell volume;platelet;C-reactive protein;erythrocyte sedimentation rate;	—

Countries

China

Contacts

Public ContactYuanchi Huang

Xi'an Honghui Hospital

huangychell@163.com18092970326

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026