Hypertriglyceridemia-Induced Acute Pancreatitis
Conditions
Interventions
standard treatment group:insulin and low molecular weight haparin
Sponsors
Center of Severe Acute Pancreatitis,Department of Critical Care Medicine, Jinling Hospital, Medical School of Nanjing University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Aged between 18 to 70 years; 2. With a primary diagnosis of HTG-AP; 3. Within 72 hours of onset, and the last blood TG>1000mg/dL (11.3mmol/L) before enrollment (data collected within 12h before randomization); 4. Organ failure (including respiratory, renal and cardio vascular systerm) as defined in the SOFA score.
Exclusion criteria
Exclusion criteria: 1. With contraindications of plasmapheresis; 2. With contraindications of insulin or low molecular weight haparin; 3. Patients are expected to die within 48 hours after enrollment; 4. Participated in other randomized controlled trials; 5. Without informed consent; 6. Pregnant or lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Organ failure free day; | — |
Secondary
| Measure | Time frame |
|---|---|
| New organ failure;Requirements for entering ICU; | — |
Countries
China
Contacts
Public ContactZhihui Tong
Center of Severe Acute Pancreatitis, Department of Critical Care Medicine, Jinling Hospital, Medical School of Nanjing University
Outcome results
None listed